Neil Redfearn's side had their defence exposed by a brace from an in-form Daryl Murphy in a performance reminiscent of their loss against Blackburn.
With Giuseppe Bellusci sidelined as a result of an injured hamstring, Redfearn was forced to start Jason Pearce alongside Liam Cooper in the heart of the defence. This was the only change from the side that took three points against Derby last weekend.
The change seemed to have little effect early on, with United taking the lead in the fourth minute. After an early long ball to Stephen Warnock, the club captain found himself free in the box and found Mirco Antenucci alone at the back post. The Italian striker had all the time in the world to convert with a simple tap-in.
The lead disappeared eight minutes later, when Daryl Murphy scored the first of his two goals on the day. Unmarked in the box, Murphy headed Luke Chambers' cross home for his 12th goal of the season.
With Leeds reeling, Warnock needlessly bundled over Paul Anderson in the box. David McGoldrick calmly stepped up and slotted the ensuing penalty kick into the left hand corner while Marco Silvestri could only watch after going to the right.
Ipswich began to dominate the game after the goal, with McGoldrick and Murphy each failing to convert goal scoring opportunities. Murphy would get his second goal of match in injury time. Finding himself alone on the right side of the box, the forward raced towards goal and shot through a befuddled Silvestri's legs for his 13th tally of the season.
The Blues put the game beyond reach just six minutes after the break. Off a corner kick, defender Tommy Smith found space and saw his near post header find the net on the opposite side of the goal.
In the end, Leeds were unable to net a consolation goal and found themselves thoroughly outmatched by an Ipswich team that remains unbeaten in their last seven matches. Their upcoming fixture against a struggling Fulham team that was hit for five against Watford gives them a good opportunity to rebound from such a tough loss.
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